全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
AMM02921G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KEAP1 Antibody.
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分子量 |
69.7kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Shuttles between cytoplasm and nucleus
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse
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克隆號(hào) |
1F10B6
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亞型 |
IgG1
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通用名 |
INRF2, KIAA0132, KLHL19
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基因ID |
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UniProt ID |
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功能 |
Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, ICC, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
IF~~1/50
FC~~1/200 - 1/400
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圖像 |
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說明書 |
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數(shù)量 |
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