品牌 |
Leading Biology | 貨號(hào) |
AMM02883G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FAS Antibody.
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分子量 |
37.7kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted. Isoform 5: Secreted.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
4F8D6
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亞型 |
IgG1
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通用名 |
APT1, FAS1, TNFRSF6
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基因ID |
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UniProt ID |
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功能 |
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
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圖像 |
Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Figure 2: Western blot analysis using FAS mAb against human FAS (AA: 87-278) recombinant protein. (Expected MW is 47.2 kDa) Figure 3: Western blot analysis using FAS mouse mAb against Hela (1), Jurkat (2) cell lysate. |
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說(shuō)明書(shū) |
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數(shù)量 |
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選擇 | 品牌 | 貨號(hào) | 產(chǎn)品名稱(chēng) | 規(guī)格 | 分類(lèi) | 研究領(lǐng)域 | 說(shuō)明書(shū) | 數(shù)量 | 目錄價(jià) | |
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¥5450.00 | 訂購(gòu) 詢(xún)價(jià) | ||
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¥6950.00 | 訂購(gòu) 詢(xún)價(jià) | ||
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¥6950.00 | 訂購(gòu) 詢(xún)價(jià) |
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