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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > CD44 Antibody (clone BU52, Azide-free)

CD44 Antibody (clone BU52, Azide-free)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM02303G 50 μg / ¥4950

CD44 Antibody (clone BU52, Azide-free)

品牌

Leading Biology

貨號(hào)

AMM02303G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD44 Antibody (clone BU52, Azide-free).

分子量

81538 Da

細(xì)胞定位

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges.

宿主

Mouse

種屬反應(yīng)性

Human

靶點(diǎn)

Epitope 1 of the CD44 molecule.

克隆號(hào)

BU52

亞型

IgG1

通用名

LHR, MDU2, MDU3, MIC4

基因ID

UniProt ID

功能

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

總結(jié)

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

IHC-P, Flo

稀釋方法

IHC-P (10 μg/ml),

圖像

Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)

Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

Flow cytometry of CD44 antibody

說明書

數(shù)量

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