品牌 |
Leading Biology |
貨號(hào) |
AMM02283G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DAPK2 / DAP Kinase 2 Antibody (clone 1B5).
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分子量 |
42898 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cytoplasmic vesicle, autophagosome lumen
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Human DAPK2
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克隆號(hào) |
1B5
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亞型 |
IgG2b
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基因ID |
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UniProt ID |
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功能 |
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation.
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總結(jié) |
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, IP
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稀釋方法 |
IF (1:100), IHC-P (10 μg/ml), WB (1:2000),
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圖像 |
Anti-DAPK2 / DRP1 antibody IHC staining of human heart.
Anti-DAPK2 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently...
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DAPK2...
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說明書 |
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數(shù)量 |
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