品牌 |
Leading Biology | 貨號 |
AMM02219G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD105 Antibody (clone 8A1).
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分子量 |
71kDa
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細胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Mouse
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種屬反應性 |
Human, Mouse, Rat, Monkey, Dog
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靶點 |
Human CD105
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克隆號 |
8A1
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通用名 |
END
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基因ID |
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UniProt ID |
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功能 |
Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
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總結 |
Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF
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稀釋方法 |
IF (1:100), IHC-P (10 μg/ml), WB (1:200-1:4000)
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圖像 |
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ENG... Western blot of extracts (35 ug) from 9 different cell lines by using anti-ENG monoclonal... Immunofluorescent staining of HeLa cells using anti-ENG mouse monoclonal antibody. |
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說明書 |
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數(shù)量 |
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