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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > CD45 Antibody (clone PD7/26/16 + 2B11)品牌 |
Leading Biology | 貨號(hào) |
AMM01966G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD45 Antibody (clone PD7/26/16 + 2B11).
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分子量 |
147kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein Membrane raft. Note=Colocalized with DPP4 in membrane rafts
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
PD7/26/16 + 2B11
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通用名 |
CD45
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基因ID |
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UniProt ID |
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功能 |
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
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總結(jié) |
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-P, IF, Flo
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稀釋方法 |
IF, IHC-P (10 μg/ml),
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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