CUL9 / Cullin 9 Antibody (clone PO69)

AMM01866G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM01866G		50 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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CUL9 / Cullin 9 Antibody (clone PO69)

品牌	Leading Biology	貨號(hào)	AMM01866G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CUL9 / Cullin 9 Antibody (clone PO69).
分子量	281kDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Mouse
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	Human PARC peptide, corresponding to human amino acids AWEAKGPNMPGSC
克隆號(hào)	PO69
通用名	H7AP1, KIAA0708, PARC
基因ID	23113
UniProt ID	Q8IWT3
功能	Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 (PubMed:24793696). Cytoplasmic anchor protein in p53/TP53- associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function (PubMed:12526791, PubMed:17332328).
總結(jié)	Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 (PubMed:24793696). Cytoplasmic anchor protein in p53/TP53- associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function (PubMed:12526791, PubMed:17332328).
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P
稀釋方法	IHC-P (10 μg/ml)
圖像	HepG2 cell extract (left lane) or NIH 3T3 cell extract (right lane) probed with monoclonal... Anti-CUL9 / Cullin 9 antibody IHC of human placenta. Anti-CUL9 / Cullin 9 antibody IHC of human prostate.
說(shuō)明書(shū)	Product Datasheet Protocol
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