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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > IL23A / IL-23 p19 Antibody (clone HLT2736)品牌 |
Leading Biology | 貨號(hào) |
AMM01841G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL23A / IL-23 p19 Antibody (clone HLT2736).
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分子量 |
21kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted. Note=Secreted upon association with IL12B
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Human recombinant p40 and p19 with elastin linker
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克隆號(hào) |
HLT2736
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通用名 |
SGRF
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基因ID |
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UniProt ID |
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功能 |
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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總結(jié) |
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P
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稀釋方法 |
IHC-P (10 μg/ml)
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圖像 |
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說明書 |
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數(shù)量 |
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