品牌 |
Leading Biology | 貨號 |
AMM01768G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD40 Antibody (clone LOB7/6).
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分子量 |
31kDa
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細胞定位 |
Antigen Cellular Localization:
Isoform I: Cell membrane; Single-pass type I membrane protein
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Dog
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靶點 |
Recognizes human CD40 cell surface antigen, a 48kD glycoprotein expressed by B lymphocytes and weakly by some monocytes. CD40 is involved in the process of B cell selection in germinal centers and is vital in T cell-B cell interactions.
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克隆號 |
LOB7/6
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通用名 |
TNFRSF5
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基因ID |
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UniProt ID |
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功能 |
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
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總結(jié) |
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-P, IP, IHC-Fr, Flo
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稀釋方法 |
Flo (20 μg/ml), IHC-Fr (1-10 μg/ml), IHC-P (10 μg/ml)
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圖像 |
Anti-CD40 antibody IHC of human spleen. |
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說明書 |
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數(shù)量 |
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