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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > TP73 / p73 Antibody (N-Terminus, clone 5B429)品牌 |
Leading Biology | 貨號 |
AMM01750G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TP73 / p73 Antibody (N-Terminus, clone 5B429).
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分子量 |
70kDa
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細胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Note=Accumulates in the nucleus in response to DNA damage
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宿主 |
Mouse
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種屬反應性 |
Human, Mouse
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靶點 |
Full-length human p73. It reacts with an epitope that is located on the N-terminal region of human p73. It does not cross react with p53.
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克隆號 |
5B429
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通用名 |
P73
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基因ID |
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UniProt ID |
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功能 |
Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
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總結(jié) |
Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, ICC, IP
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稀釋方法 |
IHC-P (5 μg/ml), WB (2 μg/ml),
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圖像 |
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說明書 |
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數(shù)量 |
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