品牌 |
Leading Biology | 貨號(hào) |
AMM02981G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MMEL1 Antibody.
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分子量 |
89.4kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type II membrane protein. Secreted. Note=A secreted form produced by proteollytic cleavage also exists.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
2D2H5
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亞型 |
IgG1
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通用名 |
MELL1, MMEL2, NEP2
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基因ID |
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UniProt ID |
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功能 |
Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond (By similarity).
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總結(jié) |
The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene. ; ;
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, FC, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
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圖像 |
Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Figure 1: Western blot analysis using MMEL1 mAb against human MMEL1 (AA: 1-107) recombinant protein. (Expected MW is 37 kDa) Figure 2: Western blot analysis using MMEL1 mAb against HEK293 (1) and MMEL1 (AA: 1-107)-hIgGFc transfected HEK293 (2) cell lysate. |
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說明書 |
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數(shù)量 |
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