品牌 |
Leading Biology | 貨號 |
AMM02677G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MDM4 Antibody.
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分子量 |
55kDa
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細胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Mouse
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種屬反應性 |
Human
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克隆號 |
2D10F4
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亞型 |
IgG1
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通用名 |
MDMX
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基因ID |
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UniProt ID |
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功能 |
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC, ICC, E
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稀釋方法 |
WB~~1/500 - 1/2000
IHC~~1/500 - 1/2000
IF~~1/200 - 1/1000
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圖像 |
Figure 1: Western blot analysis using MDM4 mouse mAb against Hela (1), A549 (2) and A431 (3) cell lysate. Figure 2: Immunohistochemical analysis of paraffin-embedded human cerebra (left) and lung carcinoma (right) tissues, showing nuclear localization with DAB staining using MDM4 mouse mAb. Figure 3: Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using MDM4 mouse mAb |
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說明書 |
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數(shù)量 |
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