品牌 |
Leading Biology | 貨號(hào) |
AMM02640G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Human P16 Antibody.
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分子量 |
16533 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
5A8A4; 3G8D12
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亞型 |
IgG1
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通用名 |
CDKN2, MTS1
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基因ID |
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UniProt ID |
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功能 |
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, E
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稀釋方法 |
WB~~1/500 - 1/2000
IHC~~1/500 - 1/2000
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圖像 |
Figure 1: Western blot analysis using P16 mouse mAb against truncated P16 recombinant protein. Figure 2: Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma (A), esophageal squamous cell carcinoma (B), hepatic cell carcinoma (C), thyroid tumor (D), breast adenofibroma (E), breast infiltrating ductal carcinoma (F), normal cerebrum tissue (G), normal colon tissue (H), normal esophageal tissue (I), showing nuclear localization using P16 mouse mAb with DAB staining. Figure 3: Immunohistochemical analysis of paraffin-embedded human spleen tissues using P16 mouse mAb. |
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說(shuō)明書 |
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數(shù)量 |
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