品牌 |
Leading Biology |
貨號(hào) |
AMM04303G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality USP5 Antibody (monoclonal) (M01).
|
分子量 |
95786 Da
|
宿主 |
mouse
|
種屬反應(yīng)性 |
Human
|
靶點(diǎn) |
USP5 (NP_003472, 71 a.a. ~ 180 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
|
克隆號(hào) |
2C8
|
亞型 |
IgG2a Kappa
|
基因ID |
|
UniProt ID |
|
總結(jié) |
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).
|
儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB, E
|
稀釋方法 |
WB~~1:500~1000
|
圖像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
Detection limit for recombinant GST tagged USP5 is approximately 0.03ng/ml as a capture antibody.
|
說明書 |
|
數(shù)量 |
|