品牌 |
Leading Biology | 貨號 |
AMM04155G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SUFU Antibody (monoclonal) (M01).
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分子量 |
53947 Da
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
SUFU (AAH13291, 181 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆號 |
1B2
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亞型 |
IgG2a Kappa
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基因ID |
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UniProt ID |
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總結(jié) |
The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
E
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圖像 |
Detection limit for recombinant GST tagged SUFU is approximately 0.1ng/ml as a capture antibody. Proximity Ligation Analysis of protein-protein interactions between STK36 and SUFU HeLa cells were stained with anti-STK36 rabbit purified polyclonal 1:1200 and anti-SUFU mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue). |
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說明書 |
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數(shù)量 |
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