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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > PAK3 Antibody (monoclonal) (M08)

PAK3 Antibody (monoclonal) (M08)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM03880G 100 μg / ￥4950

PAK3 Antibody (monoclonal) (M08)

品牌

 Leading Biology

貨號(hào)

 AMM03880G

產(chǎn)品分類(lèi)

 Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAK3 Antibody (monoclonal) (M08).

分子量
62310 Da

宿主
mouse

種屬反應(yīng)性
Human, Mouse

靶點(diǎn)
PAK3 (NP_002569, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆號(hào)
3A12

亞型
IgG2a Kappa

基因ID

UniProt ID

總結(jié)
PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, IF

稀釋方法
WB~~1:500~1000

圖像

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.53 KDa) .

PAK3 monoclonal antibody (M08), clone 3A12 Western Blot analysis of PAK3 expression in NIH/3T3 ( AMM03880G )

Immunofluorescence of monoclonal antibody to PAK3 on NIH/3T3 cell. [antibody concentration 10 ug/ml]

說(shuō)明書(shū)

數(shù)量

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