品牌 |
Leading Biology |
貨號 |
AMM03721G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KLK6 Antibody (monoclonal) (M01).
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分子量 |
26856 Da
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點 |
KLK6 (AAH15525, 91 a.a. ~ 190 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆號 |
4A10
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亞型 |
IgG2a Kappa
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基因ID |
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UniProt ID |
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總結(jié) |
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:500~1000
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圖像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .
Western Blot analysis of KLK6 expression in transfected 293T cell line by KLK6 monoclonal antibody (M01), clone 4A10.Lane 1: KLK6 transfected lysate(26.9 KDa).Lane 2: Non-transfected lysate.
Detection limit for recombinant GST tagged KLK6 is approximately 0.3ng/ml as a capture antibody.
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說明書 |
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數(shù)量 |
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