品牌 |
Leading Biology |
貨號(hào) |
AMM03665G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL18BP Antibody (monoclonal) (M05).
|
分子量 |
21099 Da
|
宿主 |
mouse
|
種屬反應(yīng)性 |
Human
|
靶點(diǎn) |
IL18BP (AAH44215, 31 a.a. ~ 194 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
|
克隆號(hào) |
2A9
|
亞型 |
IgG2b Kappa
|
基因ID |
|
UniProt ID |
|
總結(jié) |
The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternative splicing results in multiple transcript variants.
|
儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB, E
|
稀釋方法 |
WB~~1:500~1000
|
圖像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (43.78 KDa) .
Detection limit for recombinant GST tagged IL18BP is approximately 3ng/ml as a capture antibody.
|
說明書 |
|
數(shù)量 |
|