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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > HERPUD1 Antibody (monoclonal) (M04)

HERPUD1 Antibody (monoclonal) (M04)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM03618G 100 μg / ￥4950

HERPUD1 Antibody (monoclonal) (M04)

品牌

 Leading Biology

貨號(hào)

 AMM03618G

產(chǎn)品分類

 Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HERPUD1 Antibody (monoclonal) (M04).

分子量
43720 Da

宿主
mouse

種屬反應(yīng)性
Human

靶點(diǎn)
HERPUD1 (NP_055500, 74 a.a. ~ 180 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆號(hào)
2G7

亞型
IgG2a Kappa

基因ID

UniProt ID

總結(jié)
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, IHC, IP, E

稀釋方法
WB~~1:500~1000

圖像

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.51 KDa) .

HERPUD1 monoclonal antibody (M04), clone 2G7 Western Blot analysis of HERPUD1 expression in HepG2 ( AMM03618G )

Western Blot analysis of HERPUD1 expression in transfected 293T cell line by HERPUD1 monoclonal antibody (M04), clone 2G7.Lane 1: HERPUD1 transfected lysate(44 KDa).Lane 2: Non-transfected lysate.

說(shuō)明書

數(shù)量

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