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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > CD40 Antibody (monoclonal) (M01)

CD40 Antibody (monoclonal) (M01)

貨號 貨期 規(guī)格 / 價格 詢價
AMM03344G 100 μg / ¥4950

CD40 Antibody (monoclonal) (M01)

品牌

Leading Biology

貨號

AMM03344G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD40 Antibody (monoclonal) (M01).

分子量

30619 Da

宿主

mouse

種屬反應性

Human

靶點

CD40 (AAH64518, 1 a.a. ~ 151 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆號

1G1

亞型

IgG2b Kappa

基因ID

UniProt ID

總結(jié)

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

WB, E

稀釋方法

WB~~1:500~1000

圖像

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (42.35 KDa) .

Detection limit for recombinant GST tagged CD40 is approximately 0.1ng/ml as a capture antibody.

說明書

數(shù)量

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