CD44 / HCAM Std. Antibody - Without BSA and Azide

AMM01583G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM01583G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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CD44 / HCAM Std. Antibody - Without BSA and Azide

品牌	Leading Biology	貨號(hào)	AMM01583G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD44 / HCAM Std. Antibody - Without BSA and Azide.
分子量	80-95kDa
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges.
宿主	Mouse
種屬反應(yīng)性	Human, Mouse
克隆號(hào)	HCAM/1097
亞型	Mouse / IgG1, kappa
通用名	LHR, MDU2, MDU3, MIC4
基因ID	960
UniProt ID	P16070
功能	Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
總結(jié)	Recognizes a cell surface glycoprotein of 80-95kDa (CD44) on lymphocytes, monocytes, and granulocytes. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC, IF, FC
圖像	Formalin-fixed, paraffin-embedded human Tonsil stained with CD44 Monoclonal Antibody (HCAM/1097)
說(shuō)明書(shū)	Product Datasheet Protocol
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CD44 / HCAM Std. Antibody - Without BSA and Azide