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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Vimentin (Mesenchymal Cell Marker) Antibody - Without BSA and Azide

Vimentin (Mesenchymal Cell Marker) Antibody - Without BSA and Azide

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM01403G 100 μg / ￥4950

Vimentin (Mesenchymal Cell Marker) Antibody - Without BSA and Azide

品牌

 Leading Biology

貨號(hào)

 AMM01403G

產(chǎn)品分類

 Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Vimentin (Mesenchymal Cell Marker) Antibody - Without BSA and Azide.

分子量
57-60kDa

細(xì)胞定位
Antigen Cellular Localization: Cytoplasm.

宿主
Mouse

種屬反應(yīng)性
Human

克隆號(hào)
VM1170

亞型
Mouse / IgG1

基因ID

UniProt ID

功能
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

總結(jié)
This MAb reacts with a 58kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP s) such as desmin, keratin, neurofilament, and glial fibrillary acid protein.?Anti-vimentin alone is of limited value as a diagnostic tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.

形式
Liquid

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, IHC, IF, FC

圖像

Formalin-fixed, paraffin-embedded human Melanoma stained with Vimentin Monoclonal Antibody (VM1170).

Formalin-fixed, paraffin-embedded human Angiosarcoma stained with Vimentin Monoclonal Antibody (VM1170).

Formalin-fixed, paraffin-embedded human Ewing's Sarcoma stained with Vimentin Monoclonal Antibody (VM1170).

說(shuō)明書

數(shù)量

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