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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > CD57 / B3GAT1 (Natural Killer Cell Marker) Antibody - Without BSA and Azide

CD57 / B3GAT1 (Natural Killer Cell Marker) Antibody - Without BSA and Azide

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM00751G 100 μg / ¥4950

CD57 / B3GAT1 (Natural Killer Cell Marker) Antibody - Without BSA and Azide

品牌

Leading Biology

貨號

AMM00751G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD57 / B3GAT1 (Natural Killer Cell Marker) Antibody - Without BSA and Azide.

分子量

~110kDa

細(xì)胞定位

Antigen Cellular Localization: Golgi apparatus membrane; Single-pass type II membrane protein

宿主

Mouse

種屬反應(yīng)性

Human

克隆號

SPM527

亞型

Mouse / IgM, kappa

通用名

GLCATP

基因ID

UniProt ID

功能

Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

總結(jié)

Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.

形式

Liquid

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

IHC, IF

圖像

Formalin-fixed, paraffin-embedded human Tonsil stained with CD57 Monoclonal Antibody (SPM527).

說明書

數(shù)量

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