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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Alkaline Phosphatase (Placental) / PLAP (Germ Cell Tumor Marker) Antibody - Without BSA and Azide品牌 |
Leading Biology | 貨號(hào) |
AMM00716G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Alkaline Phosphatase (Placental) / PLAP (Germ Cell Tumor Marker) Antibody - Without BSA and Azide.
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分子量 |
70kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
ALPP/238
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亞型 |
Mouse / IgG2a, kappa
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通用名 |
PLAP
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基因ID |
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UniProt ID |
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總結(jié) |
PLAP is a tissue specific, trophoblast-derived, 70kDa, glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2+ metallo glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific APā€?s in humans, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous. Non-tissue specific AP is found in kidney, liver and bone. This MAb binds equally well to all common allelic variants (S, F, FS and I) of PLAP as to AP from normal human testis. This MAb can be used both as coating as well as tracer antibody in the same ELISA to detect PLAP in serum of S, F, FS and I phenotypes.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-F, IF, FC
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說明書 |
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數(shù)量 |
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