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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Alkaline Phosphatase (Intestinal) Antibody - Without BSA and Azide品牌 |
Leading Biology | 貨號 |
AMM00705G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Alkaline Phosphatase (Intestinal) Antibody - Without BSA and Azide.
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分子量 |
55kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Cow
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克隆號 |
SPM372
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亞型 |
Mouse / IgG1, kappa
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基因ID |
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UniProt ID |
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功能 |
This isozyme may play a role in skeletal mineralization.
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總結(jié) |
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-F, IF, FC
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說明書 |
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數(shù)量 |
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