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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Fibronectin (8th Type III Repeat) Antibody - Without BSA and Azide品牌 |
Leading Biology | 貨號 |
AMM00695G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Fibronectin (8th Type III Repeat) Antibody - Without BSA and Azide.
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分子量 |
220kDa (monomer); 440kDa (dimer)
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細胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix
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宿主 |
Mouse
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種屬反應性 |
Human
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克隆號 |
568
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亞型 |
Mouse / IgG1, kappa
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通用名 |
FN
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基因ID |
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UniProt ID |
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功能 |
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
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總結 |
Epitope of this MAb is located in the 8th type III repeat in the cell-binding region of fibronectin. Fibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
IHC, IF, FC
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圖像 |
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說明書 |
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數(shù)量 |
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