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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > HCC-4 / Liver Expressed Chemokine (LEC) Antibody - Without BSA and Azide

HCC-4 / Liver Expressed Chemokine (LEC) Antibody - Without BSA and Azide

貨號 貨期 規(guī)格 / 價格 詢價
AMM00393G 100 μg / ¥4950

HCC-4 / Liver Expressed Chemokine (LEC) Antibody - Without BSA and Azide

品牌

Leading Biology

貨號

AMM00393G

產品分類

Monoclonal Antibodies

研究領域

產品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HCC-4 / Liver Expressed Chemokine (LEC) Antibody - Without BSA and Azide.

分子量

11kDa

細胞定位

Antigen Cellular Localization: Secreted.

宿主

Mouse

種屬反應性

Human

克隆號

LEC66

亞型

Mouse / IgG1, kappa

通用名

ILINCK, NCC4, SCYA16

基因ID

UniProt ID

功能

Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.

總結

Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelo-suppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones. The ability of HCC-4 to markedly improve recognition of poorly immunogenic cells suggests that it could be an effective component of antitumor vaccines.

形式

Liquid

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

E

說明書

數(shù)量

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