FOXP3 (Forkhead Box Protein P3) / Scurfin Antibody - Without BSA and Azide

AMM00355G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM00355G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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FOXP3 (Forkhead Box Protein P3) / Scurfin Antibody - Without BSA and Azide

品牌	Leading Biology	貨號	AMM00355G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FOXP3 (Forkhead Box Protein P3) / Scurfin Antibody - Without BSA and Azide.
分子量	47-55kDa
細(xì)胞定位	Antigen Cellular Localization: Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00089}
宿主	Mouse
種屬反應(yīng)性	Human, Mouse, Monkey
克隆號	FXP3/197
亞型	Mouse / IgG1, kappa
通用名	IPEX
基因ID	50943
UniProt ID	Q9BZS1
功能	Probable transcription factor. Plays a critical role in the control of immune response.
總結(jié)	Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	IHC-P, IF, FC
圖像	Formalin-fixed, paraffin-embedded human Tonsil stained with FOXP3 Monoclonal Antibody (FXP3/197). Formalin-fixed, paraffin-embedded human Testicular Carcinoma stained with FOXP3 Monoclonal Antibody (FXP3/197).
說明書	Product Datasheet Protocol
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FOXP3 (Forkhead Box Protein P3) / Scurfin Antibody - Without BSA and Azide