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MUC2 (Mucin 2) Antibody - Without BSA and Azide

貨號 貨期 規(guī)格 / 價格 詢價
AMM00341G 100 μg / ¥4950

MUC2 (Mucin 2) Antibody - Without BSA and Azide

品牌

Leading Biology

貨號

AMM00341G

產品分類

Monoclonal Antibodies

研究領域

產品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MUC2 (Mucin 2) Antibody - Without BSA and Azide.

分子量

520kDa

細胞定位

Antigen Cellular Localization: Secreted. Note=In the intestine, secreted into the inner and outer mucus layers.

宿主

Mouse

種屬反應性

Human

克隆號

SPM513

亞型

Mouse / IgG1, kappa

通用名

SMUC

基因ID

UniProt ID

功能

Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.

總結

Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as ?GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.

形式

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

IHC-P, IF, FC

圖像

Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with MUC2 Monoclonal Antibody (SPM513).

說明書

數量

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