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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Cytokeratin 8 (KRT8) Antibody - Without BSA and Azide品牌 |
Leading Biology | 貨號(hào) |
AMM00310G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin 8 (KRT8) Antibody - Without BSA and Azide.
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分子量 |
52.5kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus, nucleoplasm Nucleus matrix
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Rat, Zebrafish
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克隆號(hào) |
SPM538
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亞型 |
Mouse / IgG1
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通用名 |
CYK8
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基因ID |
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UniProt ID |
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功能 |
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
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總結(jié) |
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular (?ring-like, perinuclear?) from ductal (?peripheral-predominant?) carcinoma of the breast.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-P, IF, FC
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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