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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody

CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢(xún)價(jià)
AMM01548G 7 ml / ￥4950

CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody

品牌

 Leading Biology

貨號(hào)

 AMM01548G

產(chǎn)品分類(lèi)

 Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD34 (Hematopoietic Stem Cell & Endothelial Marker) Antibody.

分子量
90-110kDa

細(xì)胞定位
Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

宿主
Mouse

種屬反應(yīng)性
Human

克隆號(hào)
HPCA1/763

亞型
Mouse / IgG1, kappa

基因ID

UniProt ID

功能
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.

總結(jié)
This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but with a lower specificity.

形式
Liquid

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
IHC, IF, FC

圖像

Formalin-fixed, paraffin-embedded human Angiosarcoma stained with CD34 Monoclonal Antibody (HPCA1/763)

Formalin-fixed, paraffin-embedded human Tonsil stained with CD34 Monoclonal Antibody (HPCA1/763)

Formalin-fixed, paraffin-embedded human Placenta stained with CD34 Monoclonal Antibody (HPCA1/763)

說(shuō)明書(shū)

數(shù)量

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