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Beta-2 Microglobulin (Renal Failure & Tumor Marker) Antibody

AMM01218G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM01218G		7 ml / ￥4950

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Beta-2 Microglobulin (Renal Failure & Tumor Marker) Antibody

品牌	Leading Biology	貨號	AMM01218G
產(chǎn)品分類	Monoclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Beta-2 Microglobulin (Renal Failure & Tumor Marker) Antibody.
分子量	12kDa
細胞定位	Antigen Cellular Localization: Secreted. Note=Detected in serum and urine
宿主	Mouse
種屬反應性	Human
克隆號	B2M/1118
亞型	Mouse / IgG1, kappa
基因ID	567
UniProt ID	P61769
功能	Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
總結	β2 microglobulin is a 12KDa protein with a pI of 5.6. Serum β2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. β2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	IHC, IF, FC
圖像	Formalin-fixed, paraffin-embedded human Cervical Carcinoma stained with Beta-2-Microglobulin Monoclonal Antibody (B2M/1118) Formalin-fixed, paraffin-embedded human Endometrial Carcinoma stained with Beta-2-Microglobulin Monoclonal Antibody (B2M/1118) Formalin-fixed, paraffin-embedded human Cervical Carcinoma stained with Beta-2-Microglobulin Monoclonal Antibody (B2M/1118)
說明書	Product Datasheet Protocol
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