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Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker) Antibody品牌 |
Leading Biology | 貨號(hào) |
AMM01147G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker) Antibody.
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分子量 |
205kDa (MHC-1) and 200kDa (MHC-2)
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細(xì)胞定位 |
Antigen Cellular Localization:
Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Thick filaments of the myofibrils
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Rat
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克隆號(hào) |
MYH11/923
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亞型 |
Mouse / IgG1, kappa
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通用名 |
KIAA0866
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基因ID |
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UniProt ID |
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功能 |
Muscle contraction.
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總結(jié) |
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC, IF, FC
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圖像 |
Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with SM-MHC Monoclonal Antibody (MYH11/923). Formalin-fixed, paraffin-embedded human Leiomyosarcoma stained with SM-MHC Monoclonal Antibody (MYH11/923). Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with SM-MHC Monoclonal Antibody (MYH11/923). |
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說明書 |
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數(shù)量 |
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