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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > MUC5AC (Mucin 5AC / Gastric Mucin) Antibody品牌 |
Leading Biology | 貨號(hào) |
AMM01094G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MUC5AC (Mucin 5AC / Gastric Mucin) Antibody.
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分子量 |
>1,000kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse, Rat, Rabbit, Monkey, Pig, Chicken, Cat
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克隆號(hào) |
45M1
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亞型 |
Mouse / IgG1, kappa
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通用名 |
MUC5
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UniProt ID |
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功能 |
Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system.
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總結(jié) |
This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).?Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC, IF, FC
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圖像 |
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說明書 |
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數(shù)量 |
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