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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Ep-CAM / CD326 (Epithelial Marker) Antibody

Ep-CAM / CD326 (Epithelial Marker) Antibody

貨號 貨期 規(guī)格 / 價格 詢價
AMM00981G 7 ml / ¥4950

Ep-CAM / CD326 (Epithelial Marker) Antibody

品牌

Leading Biology

貨號

AMM00981G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Ep-CAM / CD326 (Epithelial Marker) Antibody.

分子量

40-43kDa

細胞定位

Antigen Cellular Localization: Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction

宿主

Mouse

種屬反應性

Human

克隆號

EGP40/1120

亞型

Mouse / IgG1, kappa

通用名

GA733-2, M1S2, M4S1, MIC18, TACSTD1, TRO

基因ID

UniProt ID

功能

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.

總結(jié)

EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

形式

Liquid

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

WB, IHC, IF, FC

圖像

Formalin-fixed, paraffin-embedded human Ovarian Carcinoma stained with Ep-CAM Monoclonal Antibody (EGP40/1120).

Western Blot Analysis of HCT116 Cell Lysate using EpCAM Monoclonal Antibody (EGP40/1120)

說明書

數(shù)量

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