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Monoclonal Antibodies >
Lambda Light Chain (B-Cell Marker) Antibody品牌 |
Leading Biology | 貨號 |
AMM00908G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Lambda Light Chain (B-Cell Marker) Antibody.
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分子量 |
~22.5kDa
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
LcN-2
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亞型 |
Mouse / IgG2a, kappa
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UniProt ID |
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總結(jié) |
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, IF, FC
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圖像 |
Formalin-fixed, paraffin-embedded human Tonsil stained with Lambda Light Chain Monoclonal Antibody (LcN-2). Western Blot of human Intestinal Lysateusing Lambda Light Chain Monoclonal Antibody (LcN-2). Confocal Immunofluorescent analysis of Ramos cellsusing AF488-labeled Lambda Light Chain Monoclonal Antibody (LcN-2) (Green). DAPI was used to stain the cell nuclei (blue). |
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說明書 |
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數(shù)量 |
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