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AMP Deaminase, Isoform E (AMPD3) (Erythroid Marker) Antibody品牌 |
Leading Biology | 貨號(hào) |
AMM00776G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AMP Deaminase, Isoform E (AMPD3) (Erythroid Marker) Antibody.
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分子量 |
~90kDa
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
AMPD3/901
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亞型 |
Mouse / IgG2b, kappa
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基因ID |
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UniProt ID |
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功能 |
AMP deaminase plays a critical role in energy metabolism.
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總結(jié) |
It recognizes a protein of ~90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-F, IF, FC, ICC
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圖像 |
Formalin-fixed, paraffin-embedded human Tonsil stained with AMPD3 Monoclonal Antibody (AMPD3/901) Formalin-fixed, paraffin-embedded human Placenta stained with AMPD3 Monoclonal Antibody (AMPD3/901) |
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說(shuō)明書(shū) |
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數(shù)量 |
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