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DR5 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM03176G 100 μl / ￥4950

DR5 Antibody

品牌

 Leading Biology

貨號(hào)

 AMM03176G

產(chǎn)品分類(lèi)

 Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DR5 Antibody.

分子量
40,48 KDa

細(xì)胞定位
Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

宿主
Mouse

種屬反應(yīng)性
Human

通用名
DR5, KILLER, TRAILR2, TRICK2, ZTNFR9

基因ID

UniProt ID

功能
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. Essential for ER stress-induced apoptosis.

總結(jié)
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. Essential for ER stress-induced apoptosis.

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB

稀釋方法
WB~~1:1000

圖像

Western blot detection of DR5 in SW480,K562,HCT116 and Hela cell lysates using DR5 mouse mAb (1:1000 diluted).Predicted band size:40/48KDa.Observed band size:40/48KDa.

說(shuō)明書(shū)

數(shù)量

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