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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > MITF Antibody

MITF Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM02540G 100 μl / ¥4950

MITF Antibody

品牌

Leading Biology

貨號(hào)

AMM02540G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MITF Antibody.

分子量

58795 Da

細(xì)胞定位

Antigen Cellular Localization: Nucleus.

宿主

Mouse

種屬反應(yīng)性

Human, Mouse, Rat

靶點(diǎn)

This MITF antibody is generated from a mouse immunized with a recombinant protein of human MITF.

克隆號(hào)

1607CT834.207.47

亞型

IgG1,k

通用名

BHLHE32

基因ID

UniProt ID

功能

Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'- CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

總結(jié)

Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'- CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:2000

圖像

All lanes : Anti-MITF Antibody at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: PC-12 whole cell lysate Lane 3: NIH/3T3 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 59 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

說(shuō)明書(shū)

數(shù)量

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