CDH1 Antibody(Ascites)

AMM02452G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM02452G		100μl / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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CDH1 Antibody(Ascites)

品牌	Leading Biology	貨號(hào)	AMM02452G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDH1 Antibody(Ascites).
分子量	97456 Da
細(xì)胞定位	Antigen Cellular Localization: Cell junction. Cell membrane; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Note=Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma- catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane
宿主	Mouse
種屬反應(yīng)性	Human
靶點(diǎn)	Purified His-tagged CDH1 protein was used to produced this monoclonal antibody.
克隆號(hào)	813CT11.1.3
亞型	IgG1
通用名	CDHE, UVO
基因ID	999
UniProt ID	P12830
功能	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
總結(jié)	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:5000
圖像	CDH1 Antibody(Cat. AMM02452G) western blot analysis in MCF-7 cell line lysates (35μg/lane).This demonstrates the CDH1 antibody detected the CDH1 protein (arrow).
說明書	Product Datasheet Protocol
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