全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM00116G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Glycophorin A Antibody [Clone GPHN02].
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分子量 |
39kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein Note=Appears to be colocalized with SLC4A1
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Human erythrocytes treated with neuraminidase
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克隆號 |
GPHN02
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亞型 |
IgM, kappa
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通用名 |
GPA
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基因ID |
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UniProt ID |
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功能 |
Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV).
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總結(jié) |
Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A. It reacts with a peptide epitope on the extracellular domain of human glycophorin. Glycophorin A is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorins acts as the receptor for Sandei virus and parvovirus.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC, IF
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說明書 |
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數(shù)量 |
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