品牌 |
Leading Biology | 貨號(hào) |
AMM02506G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VWF Antibody.
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分子量 |
309265 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
This antibody is generated from a mouse immunized with .VWF recombinant protein.
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克隆號(hào) |
907CT12.1.9
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亞型 |
IgG1
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通用名 |
F8VWF
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基因ID |
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UniProt ID |
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功能 |
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
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總結(jié) |
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, FC, E
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稀釋方法 |
FC~~1:100
IHC-P~~1:25
WB~~1:1000
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圖像 |
Flow cytometric analysis of K562 cells using VWF(green, AMM02506G) compared to an isotype control of mouse IgG1(blue). AP20600c was diluted at 1:100 dilution. An Alexa Fluor? 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody. Immunohistochemical analysis of paraffin-embedded H. kidney section using VWF( AMM02506G). AMM02506G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-mouse IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining. Western blot analysis of lysate from VWF protein, using VWF Antibody(AMM02506G). AMM02506G was diluted at 1:1000. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 35μg. |
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說明書 |
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數(shù)量 |
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