MVP Antibody (N-term) (Ascites)

AMM02437G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM02437G		0.1 ml / ￥4950

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安諾倫（北京）生物科技有限公司

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MVP Antibody (N-term) (Ascites)

品牌	Leading Biology	貨號(hào)	AMM02437G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MVP Antibody (N-term) (Ascites).
分子量	99327 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus, nuclear pore complex. Note=5% found in the nuclear pore complex. Translocates from the nucleus to the cytoplasm upon EGF treatment
宿主	Mouse
種屬反應(yīng)性	Human
免疫原	12-39 aa
靶點(diǎn)	This MVP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human MVP.
克隆號(hào)	599CT2.4.1
亞型	IgG1
通用名	LRP
基因ID	9961
UniProt ID	Q14764
功能	Required for normal vault structure. Vaults are multi- subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo- cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
總結(jié)	This gene encodes the major vault protein which is a lungresistance-related protein. Vaults are multi-subunit structuresthat may be involved in nucleo-cytoplasmic transport. This proteinmediates drug resistance, perhaps via a transport process. It iswidely distributed in normal tissues, and overexpressed inmultidrug-resistant cancer cells. The protein overexpression is apotentially useful marker of clinical drug resistance. This geneproduces two transcripts by using two alternative exon 2 sequences;however, the open reading frames are the same in both transcripts.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:100~1600
圖像	MVP Antibody (N-term)(Ascites)(Cat. AMM02437G) western blot analysis in Hela cell line lysates (35μg/lane).This demonstrates the MVP antibody detected the MVP protein (arrow).
說(shuō)明書	Product Datasheet Protocol
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