HGF Antibody

AMM02413G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM02413G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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HGF Antibody

品牌	Leading Biology	貨號	AMM02413G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HGF Antibody.
分子量	83134 Da
宿主	Mouse
種屬反應(yīng)性	Human
免疫原	521-554 aa
靶點	This HGF antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 521-554 amino acids from human HGF.
克隆號	489CT6.12.6
亞型	IgG1
通用名	HPTA
基因ID	3082
UniProt ID	P14210
功能	Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.
總結(jié)	Hepatocyte growth factor regulates cell growth, cellmotility, and morphogenesis by activating a tyrosine kinasesignaling cascade after binding to the proto-oncogenic c-Metreceptor. Hepatocyte growth factor is secreted by mesenchymal cellsand acts as a multi-functional cytokine on cells of mainlyepithelial origin. Its ability to stimulate mitogenesis, cellmotility, and matrix invasion gives it a central role inangiogenesis, tumorogenesis, and tissue regeneration. It issecreted as a single inactive polypeptide and is cleaved by serineproteases into a 69-kDa alpha-chain and 34-kDa beta-chain. Adisulfide bond between the alpha and beta chains produces theactive, heterodimeric molecule. The protein belongs to theplasminogen subfamily of S1 peptidases but has no detectableprotease activity. Alternative splicing of this gene producesmultiple transcript variants encoding different isoforms. [providedby RefSeq].
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	All lanes : Anti-Human HGF C-term at 1:1000 dilution Lane 1: HepG2 whole cell lysate Lane 2: Ramos whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 83 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
說明書	Product Datasheet Protocol
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