全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
AMM02358G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CDC25C Antibody (ascites).
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分子量 |
53365 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
This CDC25C monoclonal antibody is generated from mouse immunized with CDC25C recombinant protein.
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克隆號(hào) |
233CT9.6.6
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亞型 |
IgG1,k
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基因ID |
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UniProt ID |
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功能 |
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.
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總結(jié) |
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq].
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000~8000
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圖像 |
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說明書 |
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數(shù)量 |
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