品牌 |
Leading Biology | 貨號 |
AMM02617G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Fibulin 5 Antibody.
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分子量 |
50180 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted Secreted, extracellular space, extracellular matrix. Note=co-localizes with ELN in elastic fibers.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
3F8D5; 7F8D5
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亞型 |
Ig M
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通用名 |
DANCE
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基因ID |
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UniProt ID |
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功能 |
Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823).
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1/500 - 1/2000
IHC~~1:200~~1000
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圖像 |
Figure 1: Western blot analysis using fibulin5 mouse mAb against truncated fibulin5 recombinant protein (1) and Hela cell lysate (2). Figure 2: Immunohistochemical analysis of paraffin-embedded Human pancreas carcinoma (left) and breast carcinoma (right) tissue, showing membrane and cytoplasmic (pancreas carcinoma) localization, membrane (breast carcinoma) localization using EphB4 mouse mAb with DAB staining. |
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說明書 |
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數(shù)量 |
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