CD3 Antibody (Clone OKT3)

AMM00016G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM00016G		100 μg / ￥4950

大規(guī)格詢價(jià)

1 Images

訂購信息

安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
Inquiry@annoron.com

全國授權(quán)代理商

CD3 Antibody (Clone OKT3)

品牌	Leading Biology	貨號(hào)	AMM00016G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD3 Antibody (Clone OKT3).
分子量	20469 Da
細(xì)胞定位	Antigen Cellular Localization: Membrane; Single-pass type I membrane protein
宿主	Mouse
種屬反應(yīng)性	Human
靶點(diǎn)	CD3
克隆號(hào)	OKT3
亞型	Mouse IgG2a, kappa
通用名	T3G
基因ID	917
UniProt ID	P09693
功能	The CD3 complex mediates signal transduction.
總結(jié)	CD3 (T3), a complex T cell marker, is known to associate noncovalently with the a/b or g/z heterodimer of the T cell antigen receptor (TCR) to form the most complex transmembrane (TM) receptor structures. Structurally, CD3 consists of four distinct membrane glycoprotein isoforms (CD3g, CD3e, CD3s and the zeta chain) to generate activation signals. CD3 is specially engaged in antigen recognition and is known to play an important role in mediating signals that are critical for T cell development in the thymus, proliferation, and induction of T cell-mediated immune responses against infectious agents and also in the differentiation of T cells into effector and memory populations. CD3 usually expresses in the cytoplasm of prothymocytes, and on the surface of about 95% of thymocytes, but cytoplasmic CD3 is lost as the cells differentiate into medullary thymocytes. Apart from its role as an important marker in the classification of malignant lymphomas and lymphoid leukemia, CD3 can also be useful for the identification of T cells in celiac disease, lymphocytic colitis and colorectal carcinomas associated with loss of a mismatch repair protein. CD3 indirectly plays an important role in immunomodulation whereas the anti-CD3 antibody may be used in in vitro Treg assays to generate effector T cells.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	FC
圖像	Cell surface flow analysis of CD3 in 10^6 human PBMC using CD3 Ab at 0.2 g. Green represents isotype control; red represents anti-CD3 antibody.
說明書	Product Datasheet Protocol
數(shù)量

加入購物車詢價(jià)

上一產(chǎn)品：IL-10 Antibody 下一產(chǎn)品：CD46 (Membrane Cofactor Protein) Antibody - With BSA and Azide

熱銷產(chǎn)品

產(chǎn)品添加成功！

購物車已有 0 件產(chǎn)品

繼續(xù)訂購查看訂購單

加入詢價(jià)單成功！

詢價(jià)單已有 0 件產(chǎn)品

繼續(xù)詢價(jià) 查看詢價(jià)單

選擇	品牌	貨號(hào)	產(chǎn)品名稱	規(guī)格	分類	研究領(lǐng)域	說明書	數(shù)量	目錄價(jià)
1	Leading Biology	APG01369G	VEGF (Vascular Endothelial Growth Factor) Antibody - Without BSA and Azide	100 μg	Monoclonal Antibodies				￥4950.00	訂購詢價(jià)
2	Leading Biology	AMM07627G	RIN2 Antibody (monoclonal) (M01)	100 μg	Monoclonal Antibodies				￥4950.00	訂購詢價(jià)
3	Leading Biology	APR15980G	FGG Antibody	100 μl	Monoclonal Antibodies				￥5450.00	訂購詢價(jià)
4	Leading Biology	AMM05161G	GOB5 / CLCA1 Antibody (clone 1C4)	50 μg	Monoclonal Antibodies				￥5450.00	訂購詢價(jià)
5	Leading Biology	APR17667G	ORAI1 Antibody [3F6H5]	0.1 mg	Monoclonal Antibodies				￥6950.00	訂購詢價(jià)
6	Leading Biology	APR11118G	HIV-1 p24 Antibody [7F4] (biotin)	0.1 mg	Monoclonal Antibodies				￥6950.00	訂購詢價(jià)

最新加入的商品

最新加入的商品

全部產(chǎn)品分類