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PAX7 (Rhabdomyosarcoma Marker) Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號(hào) |
AMM01163G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PAX7 (Rhabdomyosarcoma Marker) Antibody - With BSA and Azide.
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分子量 |
57kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
PAX7/1187
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亞型 |
Mouse / IgG1, kappa
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通用名 |
HUP1
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基因ID |
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UniProt ID |
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功能 |
Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation.
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總結(jié) |
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC
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圖像 |
Formalin-fixed, paraffin-embedded human Rhabdomyosarcoma stained with PAX7 Monoclonal Antibody (PAX7/1187). Formalin-fixed, paraffin-embedded human Testicular Carcinoma stained with PAX7 Monoclonal Antibody (PAX7/1187). |
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說(shuō)明書 |
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數(shù)量 |
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