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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > c-Myc Oncoprotein Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號 |
AMM01134G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality c-Myc Oncoprotein Antibody - With BSA and Azide.
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分子量 |
62-64kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus, nucleoplasm. Nucleus, nucleolus
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
MYC909
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亞型 |
Mouse / IgG1, kappa
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通用名 |
BHLHE39
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基因ID |
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UniProt ID |
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功能 |
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.
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總結(jié) |
It recognizes a transcription factor of 64-67kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Rearrangement of the MYC gene is found in 3% to 16% of diffuse large B-cell lymphoma (DLBCLā€?s) and in nearly 100% of Burkitt lymphomas (BL). Identifying MYC status is important in establishing final diagnosis of DLBCL, BL, or B-cell lymphoma, with features intermediate between DLBCL and BL as well as in differential diagnoses of the lymphomas.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC, IF, FC
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圖像 |
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說明書 |
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數(shù)量 |
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