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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > MUC6 (Mucin 6 / Gastric Mucin) Antibody - With BSA and Azide品牌 |
Leading Biology | 貨號 |
AMM01124G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MUC6 (Mucin 6 / Gastric Mucin) Antibody - With BSA and Azide.
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分子量 |
252kDa
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細胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Mouse
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種屬反應性 |
Human
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克隆號 |
MUC6/916
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亞型 |
Mouse / IgG1, kappa
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基因ID |
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UniProt ID |
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功能 |
May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis.
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總結 |
The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC, IF, FC
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圖像 |
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說明書 |
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數(shù)量 |
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